Showing posts with label corona virus. Show all posts
Showing posts with label corona virus. Show all posts

Friday, June 19, 2020

Dexamethasone: Is there a cure for the coronavirus?

Dexamethasone: Is there a cure for the coronavirus?


The Coronavirus, which started in Wuhan, China, has infected more than 8.1 million people worldwide and caused more than 440,000 deaths. COVID 19, which has affected the whole world, has infected more than 6,000 people in Nepal and 20 people have died. Of course, the good news is that Corona's fears are weakened by the long-term downturn and the economic problems she has caused, or she is forced to return to work in the crisis.

News of the vaccination and treatment of COVID 19 has raised hopes from time to time. The virus, which was discovered in December 2019, has managed to embarrass the world in a short period. Not many great studies and researches have been done in this short period. But many studies are ongoing. Tenofovir used for HIV / AIDS and hydroxychloroquine used for malaria were very popular. US President Donald Trump also made public the use of hydroxychloroquine, which has since been discontinued in the United States because of its negative effects. Recently, there have been reports of permethrin and now dexamethasone being effective.
The medicine should not be used, the immune system should be increased. So it is not uncommon to hear about the need to eat vitamin C, garlic, ginger, and yoga, and exercise. To prevent this, news of vaccine production and its study is also coming. It has also been reported that some vaccines are being studied and produced simultaneously.


Not only modern medical science but also homeopathic and ayurvedic treatment methods have explored various treatments. No matter how many experts claim to be completely cured, the world has not readily accepted it. Because the world seeks the results of the study. Now a good result has come. Probably the most infected participant in the study for COVID 19, this study showed that dexamethasone, a type of steroid available in our Nepali pharmaceutical market, was a great success.

Experts in the UK say that dexamethasone, a cheap drug available worldwide, has helped prevent serious corona infections. They say that even small doses of dexamethasone steroid can prevent serious infections. Research claims that the death rate of patients placed on ventilators is one-third and that one in five patients given oxygen is protected. Researchers at the University of Oxford administered dexamethasone to 2,000 hospitalized patients, comparing more than 4,000 patients who had not used the drug, the BBC reported. The study found that ventilator mortality rates dropped from 40 percent to 28 percent.


According to lead researcher Professor Peter Horby, it is the only drug that reduces the risk of death from infection. It is also a great success and achievement in corona treatment. However, Professor Horby has made it clear that the drug is of no benefit to the general population and is important for those with respiratory problems.

Although there has been an increase in the number of COVID 19 infections in recent times, there has been a significant reduction in the complexity of those infected. There has also been a reduction in deaths due to COVID 19 infections. Although the number of infected people is high in India, Russia, and Nepal, the death rate due to the infection is lower than in Europe and the United States. In this case, the efficacy of dexamethasone produced in our country will definitely give positive results.


Dexamethasone is a steroid that reduces inflammation caused by cavities and other causes, especially those of the pharynx and trachea, so it only benefits those with respiratory problems. It is not uncommon for the general public to avoid rage by eating this, so social distance, proper use of masks, and handwashing habits should not be forgotten to avoid COVID 19.

Sunday, May 31, 2020

Latest information on Corona-virus

6 million 54 thousand infected worldwide from Corona, 2.562 million more cured (how many in which country)

The global pandemic corona virus (Covid-19) has so far infected 6 million 54 thousand 187 people worldwide. According to Johns Hopkins University, 2.562 million of those infected have recovered.

The most contagious cases have been reported in the United States. As of Sunday morning, 1,769,776 infections had been confirmed in the United States. Similarly, 4 lakh 16 thousand 461 have been cured.

The death toll in the United States is also high. So far, 133,758 people have lost their lives in the United States. Similarly, 500,000 people have been found infected in Brazil. So far, 4,98,440 infected people have been found in Brazil. Of them, 2 lakh 892 have recovered and 28 thousand 834 have died.

After Brazil, Russia has seen many infections. So far, 396,575 people have been found infected in Russia. Of those infected, 4,555 have died and 1,67,469 have been cured. A recent decline in infection rates has so far confirmed 274,219 cases of the virus in the UK. Of them, 1,173 have recovered and 38,458 have lost their lives. Corona, which has been rampant since late December, has so far affected 188 countries. So far, 368,711 lives have been lost in these countries.

Figures for the ten most infected countries

America
Infected: 17,69,776
Deaths: 1,03,758
Healing: 4,16,461

Brazil
Infected: 4,98,440
Deaths: 28,834
Healing: 2,00,892

Russia
Infected: 3,96,575
Deaths: 4,555
Healing: 1,67,469

United Kingdom
Infected: 2,74,219
Deaths: 38,458
Healing: 1,173

Spain
Infected: 2,39,228
Deaths: 27,125
Healing: 1,50,376

Italy
Infected: 2,32,664
Deaths: 33,340
Healing: 1,55,633

France
Infected: 1,88,752
Deaths: 28,774

Healing: 68,386

Germany
Infected: 1,83,189
Deaths: 8,530
Healing: 1,64,908

India
Infected: 1,81,827
Deaths: 5,185
Healing: 86,936

Turkey
Infected: 1,63,103
Deaths: 4,515
Healing: 1,26,984

(Source: Johns Hopkins University)


Corona outbreak: This is the latest epidemic in the world

As of this writing, 371,006 people have died and 6,160,295 have been infected in the world due to the corona virus epidemic, which has become a major challenge for the world in the field of health.

Similarly, 27 lakh 38 thousand 284 people have recovered after health treatment while the health condition of 53 thousand 515 people in the world is critical. Outbreaks of the corona virus, which has spread to 213 countries, have killed 15,557 people in the United States and infected 1,816,820.

There, 5 lakh 35 thousand 238 people have recovered after health treatment and 17 thousand 163 people are in critical condition.

In Brazil, 4,99,966 people have been infected so far and 28,849 people have died. Similarly, 15 people have died and 1,526 new infections have been added today. In Brazil, 25,371 people have recovered after receiving medical treatment, while 8,318 are in critical condition.

In Russia, 4,555 people have died and 3,96,575 have been infected with the corona virus.

There, 1,67,469 people have recovered after health treatment and 2,300 are in critical condition.

In Spain, 27,125 people have died and 2,86,308 have been infected with the corona virus.

There, 196,958 people have recovered after receiving medical treatment while the health condition of 617 people is critical.

In the UK, the corona virus has so far killed 38,376 people and infected 272,826. The health condition of 1,559 people there is critical.

In Italy, 33,340 people have died and 232,664 have been infected with the corona virus. There, 155,633 people have recovered after receiving medical treatment while the health condition of 450 people is critical.

In France, the corona virus has so far killed 28,771 people and infected 188,625. There, 68 thousand 268 people have recovered after health treatment and 1 thousand 325 people are in critical condition.

In Germany, the corona virus has killed 8,600 people and infected 183,294 so far. There, 1,64,900 people have recovered after receiving medical treatment while the health condition of 720 people is critical.


Similarly, 5,185 people have died and 182,143 have been infected with the corona virus in neighboring India so far. There are 316 new infections today. In India, 86,984 people have recovered after receiving medical treatment, while 8,944 are in critical condition.

According to WorldDometer, 4,515 people have died and 1,63,103 have been infected with the corona virus in Turkey. Similarly, 126,984 people have recovered after receiving medical treatment while the health condition of 649 people is critical.

In Peru, 4,371 people have died so far due to the corona virus epidemic

A total of 155,671 people have been infected. There, 66,447 people have recovered after receiving medical treatment while the health condition of 960 people is critical.

In Iran, 7,734 people have died and 148,950 have been infected with the corona virus. There, 116,827 people have recovered after medical treatment and 2,533 people are in critical condition.

In Canada, 7,073 people have died and 90,190 have been infected. There, 48,103 people have recovered after medical treatment and 1,618 people are in critical condition.

In Mexico, the corona virus has so far killed 9,779 people and infected 87,512. There have been 364 deaths so far today and 2,885 new infections have been added today. In Mexico, 61,871 people have recovered and 378 are in critical condition.


Similarly, two more corona infections have been confirmed in China today. There have been 4,634 deaths and 83,001 infections. There, 78,304 people have recovered after health treatment and the health condition of 3 people is critical.

Similarly, 1,483 people have died and 69,496 have been infected in Pakistan so far. Today alone, 88 people have died and 3,039 new infections have been added. There, 25,271 people have recovered after receiving medical treatment while the health condition of 111 people is critical.

In Belgium, 9,453 people have died so far and 58,186 have been infected. There, 15,769 people have recovered after receiving medical treatment while the health condition of 73 people is critical.

In the Netherlands, 5,951 people have died so far and 46,257 have been infected. The health condition of 170 people there is critical.

In the last 24 hours, 500 people have died worldwide and 9,812 new infections have been added.



Get latest information on Corona-virus.

Tuesday, May 19, 2020

Is Covid-19 really that deadly?

In some people, this can lead to life-threatening complications.
This article looks at COVID-19 fatalities and most at-risk groups.
It also explores what the disease does to the body and how it compares to flu and acute acute respiratory syndrome (SARS).




For more information on the COVID-19 outbreak, visit our Coronavirus Hub and follow our live update page. Older people and those with current health conditions are at higher risk for serious complications, which can be fatal. According to the World Health Organization (WHO), 80% of people who develop the disease have mild to moderate symptoms and recover completely without the need for hospital treatment. 1 in 5 people will experience a serious illness. Older people may develop serious symptoms, such as ongoing health conditions, Some severe COVID-19 symptoms include difficulty breathing and feeling of chest pressure.
COVID-19 can cause serious and sometimes life-threatening problems, including:
The novel coronavirus enters the body through the eyes, nose or mouth. The virus then travels to the lungs and stimulates the airway layer. This inflammation irritates the surrounding nerves and causes coughing. The virus then spreads to the s lung and causes infection and damage, reducing the supply of oxygen to the bloodstream. When the oxygen level in the bloodstream decreases, the heart has to work hard to supply enough oxygen to the organs and the rest of the body. Meanwhile, the immune system is working to fight off the infection, and in doing so it can cause inflammation throughout the body. This inflammation lowers blood pressure, causing the heart's organs to pump oxygen. Lung enlargement of the lungs or pneumonia due to ung lungs. Pneumonia progresses to lung failure, in which case a person may need a ventilator to breathe. In people with current damage to the heart or the lungs, these problems can be fatal. Older people are at greater risk for serious complications due to decreased elasticity in lung tissue and less robust immune function.
The mortality rate of COVID-19 varies depending on where in the world a person is, their age and whether they have health problems.
The mortality rate of COVID-19 is generally higher in the older population. The state of the local or national health system also affects mortality. If hospitals are overwhelmed with severe cases of COVID-19, they may not have the resources to deal with them. It is important to note that the number of COVID-19 trials in a given area can significantly affect mortality data. Case - Mortality Ratio refers to the mortality ratio among those with confirmed COVID-19.



Current reports indicate that in the United States, the case-to-death ratio is 5.9%.
As most people recover with mild cases of COVID-19, this number will decrease with increasing testing. However, among the elderly and those with health conditions, deaths may be higher. The symptoms of COVID-19 are similar to the symptoms of the flu, and both cause respiratory disease. However, a person develops flu symptoms more quickly than COVID-19 symptoms. Doctors refer to the time between the onset of the infection and the symptoms that occur during the incubation period. The flu lasts only a few days, but the symptoms of COVID-19 can take up to 2 weeks. Flu symptoms are mild to some, and to others they can be severe and life-threatening.
According to WHO, current research on the severity of COVID-19 suggests:
15% of cases are severe, and people need oxygen support 5% of cases are significant, and people need mechanical ventilation. This suggests that COVID-19 may be more severe or more severe than the flu. Other research suggests that the flu spreads faster than COVID-19. Additionally, COVID-19 affects fewer children than the flu. Overall, the global mortality rate of COVID-19 is higher than the flu. The reported death toll was 3-4% in reported cases. For comparison, the seasonal flu mortality rate is generally less than 0.1%, although this varies depending on health care access. However, due to the large number of asymptomatic and mild cases, most COVID-19 cases have not been reported, meaning mortality rates are likely to be very low.
Learn more about the difference between COVID-19 and the flu.
Another type of disease caused by coronavirus is SARS. Between 2002 and 2004, the spread of SARS in China spread to other countries. SARS can also cause serious problems such as pneumonia and severe breathing problems. According to the National Foundation for Infectious Diseases, the SARS mortality rate is approximately 10%. Although more research is needed, COVID-19 can spread faster than SARS, although it may reduce the likelihood of serious disease. There have been no reports of SARS in humans since 2004. Most people with COVID-19 experience mild to moderate symptoms and most recover without the need for hospital treatment. For some people, including the elderly and ongoing health conditions, COVID-19 can cause serious symptoms and, at times, become a serious threat.



One good way to prevent infection is to prevent COVID-19.
As the coronavirus novel spreads around the world, people and businesses are locked in our communities and across the United States, the virus is clearly feared. But of all the many viruses that can infect humans, what is the most deadly epidemic in a century? The virus that causes COVID-19 is not very lethal. Coronaviruses that cause Acute Acute Respiratory Syndrome (SARS) and Middle East Respiratory Syndrome (MERS) cause 10% of infections and 30% to 40% of cases, respectively. Scientists are not sure that COVID-19 is nearly 10 times more deadly than seasonal flu, causing 0.1% of infected people to die until the tests are widespread.
Farhall, MD, Professor of Medicine and Molecular Biology and Biochemistry and Head of Infectious Diseases at the UCI School of Medicine. After collecting data on hotspots around the world, Fortale hopes today we can reduce deaths. Klein, professor of infectious diseases at UCI School of Medicine. Buchmeier believes that the virus, although fatal, is considered an epidemic of seasonal flu, in which one person infects another two or three. In contrast, with Measles, a person infects 18, or chicken pox, a person 12. However, these two most contagious diseases can be controlled by vaccination. But this is a virus that has never been seen in humans, so no person gets immunity.
It can easily spread from one person to another in the form of influenza and infect the upper respiratory system, making it very dangerous. The COVID-19 virus spreads through the upper airways - including the mouth and nose - by coughing, sneezing, huffing, and puffing, and is loud, according to Fortale. Furthermore, we are discovering that the virus is accidentally spreading a few days before infected people begin to experience symptoms. Neither SARS nor MERS can be easily or widely disseminated.
This allows the virus to enter the cells quickly, gain a firm grip, and spread quickly throughout the body. The virus also attacks the lower respiratory tract - bronchial tubes and s lungs, where it causes pneumonia. This triggers an inflammatory response as the body tries to fight off the attackers. In some people - about 15% - this immune response initiates a cyclic transgression of the body's immune system called a cytokine storm. "Not only can you cause serious damage to the lungs, it may or may not be a direct cause of the virus," Fortale said. Fortale said some people were seriously ill or died. Researchers have observed that other coronaviruses provoke similar cytokine overexpression.



Age, sex, and chronic condition increase the risk
The mortality rate is higher among those over 70, and mortality increases with age, Fortel said. Obesity and other chronic conditions - such as high blood pressure, diabetes and the underlying heart, lungs and kidney disease - increase the risk of serious infections, Fortis said. The prevalence of these diseases in the elderly may be higher in the elderly and in some people the onset of dementia is related to the symptoms they experience, which can have devastating effects on the virus in nursing and care homes. Adding although doctors are still unaware, research has shown that cytokine overexpression patterns are based on age and sex with other coronaviruses. Fortale and Buchmeier, members of the UC Irvine Center for Virus Research, are now in the news, and the subject of the UCI Health Clinical Trial is promising to treat COVID-19.



Monday, May 18, 2020

Should Nepalese be worried about the coronavirus?

The outbreak of the 2019 novel coronavirus in China, also known as the Wuhan Coronavirus, has now affected 17 countries.
There are approximately 6,000 cases in China with the majority being diagnosed. Total casualties have crossed 130, most of them in Wuhan, in Hubei Province. Nepal has recorded its first confirmed case: a student studying in China who went to Nepal when diagnosed. Coronavirus family viruses have historically caused respiratory infections in human populations worldwide.




The most recent outbreaks include acute acute respiratory syndrome (SARS) in 2002 and Middle Eastern respiratory syndrome (MERS) in 2012.
Both have affected thousands of people and in some cases can be fatal. SARS killed 10% of infected people, while MERS was fatal in 37% of the infected population. The current death rate due to Wuhan coronavirus is 2.2%. If we reverse this number, 98 percent of people infected with this virus will not die. Given the low mortality rate compared to previous coronavirus outbreaks, why is there so much concern about this outbreak?
The first reason is that the Wuhan Coronavirus is a ‘novel’.
The term is used to refer to a new species in viral epidemiology that has never been found in the population. Therefore, scientists do not know enough about the symptoms of the virus and provide public health indications about treatment.
Second, unlike SARS and MERS, the incubation period of the virus is up to 14 days, and asymptomatic individuals can spread the disease to others.
Infected individuals who show development may also continue to spread the virus. The R0 (n r naught ') value of this virus is estimated to be 3, which means that the infected person transmits on average three more people. It is believed to have a high infectivity number, but it is still lower than SARS or MERS. Chinese authorities have taken tough steps in Wuhan to stop the spread of the virus. However, this may not be enough as most infected people may be out of the city until they take action. Wuhan's population is 10 million, and many begin this week's Chinese New Year. According to experts at Imperial College in London, the number of infected populations is less than about 100,000. Therefore, we can expect more cases around the world as infected people spread and transmit the disease.



However, the question has arisen once again about how many people have been infected so far.
The virus may be spreading, but not the cause of many deaths?
Nepal has a common outbreak of respiratory diseases such as seasonal influenza, 'avian influenza' and 'swine flu'. Nepali media often report cases of ‘unknown viral disease’. The Nepalese government set up screening centers for coronaviruses at airports and border posts before the first infected person was diagnosed in Tibet. The National Public Health Laboratory is working with private hospitals and laboratories and technical assistance from the World Health Organization (WHO) to make timely and accurate diagnosis of Wuhan coronaviruses. These cases are referred to the Sukhraj Tropical Infectious Diseases Hospital and are monitored by the Department of Epidemiology and Disease Control in the country.
The Ministry of Health and Population has ordered all private hospitals in the country to be on standby if ventilator-supported ICUs are needed. The state mechanism seems to have learned from the vulnerabilities previously seen during the SARS and H1N1 (swine flu) outbreaks. However, the exact clinical diagnosis of the disease is a challenge, as people who are infected with non-symptomatic phosphoses are more likely to be infected with other viruses, such screening is the only way to identify the maximum number of cases entering the country and prevent the population from getting infected.



There have been no cases of coronavirus infection since January 25 in Nepal.
The first case has only been reported to date. The global media reporting of the outbreak is more focused on malignancy than recovery, and the WHO fails to note that the Wuhan coronavirus outbreak with its expertise and access to data has not yet declared a public health emergency. The experience of making a 'premature and hasty' decision to end the 2009 influenza A (or H1N1) - or swine flu - is still a pandemic, at which point the
WHO decided to take a close look at the situation. 
WHO is focusing on China as a priority over the action, while observing the rest of the world. This does not mean that we can be complacent, because the risk of mutation in the more severe form of the virus is real. However, this also does not help to be afraid. We need to look at the numbers, listen to the experts in this field and move on accordingly. After the end of the week, several high-level coordination committees, led by Deputy Prime Minister and Defense Minister Ishwar Pokharel, made several important decisions aimed at limiting the spread of
Travelers from more than 50 countries in Nepal, Europe, Britain, the Gulf and West Asia have been banned; Nationwide secondary education exams are postponed; Asked to close all gyms, health clubs, movie theaters, and dance bars; And all meetings of more than 25 people are banned.
Civil Aviation Minister Yogesh Bhattarai told the Post on Wednesday, "These strong measures have been taken based on the global impact of the coronavirus, the fear it has created and While these measures are welcomed, many public health officials fear they may not be enough and the public is not sure that the government is doing enough. Sundar Mani Dixit's video has criticized the government's response that the government is not conducting enough tests as the test kit is not viral. Despite a conspiracy theorist signaling for Dikshit, especially the claim that the test kits are being saved for 'VIPs', the video is taken aback by Nepal's lack of confidence in the dense urban development, poor security measures and health infrastructure. As of March 20, only 546 Nepalis were tested for Kovid-19, excluding adverse cases in January, according to the Ministry of Health and Population.



Current screening procedures include assessing whether patients have a fever with severe respiratory symptoms or have a surgical condition; And then they are assessing whether Kovid-19 may be in the 14 days they are performing, or in the affected country.
Fever is being tested for those who arrive in Nepal, and when they show no symptoms, they are asked to self-confine. If there is fever, they are left alone and sent to a designated hospital. But the airport has suffered long-term institutional and infrastructure failures. On March 9, the Diplomat reported that 13 health workers at the Tribhuvan airport were inadequate to check passengers coming from China, South Korea, Hong Kong, Thailand, Malaysia, Japan. Some travelers skip the screening process due to the limited number of health workers," one passenger told the publication.
On March 18, The Himalayan Times reported that incoming travelers were not being properly investigated and many were not being asked to remain in self-restraint. Nepal's hospitals and laboratories are also pre-equipped, first to screen potential patients, then to isolate them, and then to provide adequate care. Nepal Public Health Laboratory officials told the Post that they had only 1,000 test kits.
As of March 20, more than half of them were used and it is unclear whether they received the 5,000 kits they sought from the WHO.
On March 19, the Medical Council of Nepal urged all hospitals, private and public, to set up more than 100 beds with special fever clinics, and urged everyone to conserve resources for the outbreak, with health workers postponing elective surgery to ensure safety. Decrease. Unnecessary congestion in hospitals and treatment centers.
Kathmandu is one of the most densely populated cities in the region and the spread of it will increase health care facilities quickly. The Covid-19 mortality rate is not very high - revised from the initial estimate of 3.4 percent to less than 1 percent - but when coronavirus patients come to hospitals, those who need immediate medical care do not need care. .